高血壓 高尿酸 慢性腎病 胰島素 https://2019medicinenote.blogspot.com/2019/12/blog-post_57.html . 糖尿病相關筆記~目錄 https://2019medicinenote.blogspot.com/2020/01/blog-post_4.html

2025年10月30日 星期四

血小板低下輸血條件 Platelet Transfusion Threshold

2025-10-30 16:55
剛接到檢驗報告異常. 血小板僅12K.查詢一下輸血小板輸血條件
原則上. 若無症狀. 單純體檢或健檢發現異常
一萬以下考慮輸血小板.


Platelet Transfusion 2024 Jun 6
作者 Ankit Agarwal; Atif I. Khan; Faiz Anwer.僅節錄部分內容.
中文使用google翻譯

出血患者的血小板輸注閾值
血小板輸注閾值指導根據出血嚴重程度和臨床情況做出輸注決策。以下出血情況需要治療:
血小板計數低於 50,000 個/μL 且伴隨嚴重出血,包括瀰漫性血管內凝血;
血小板計數低於 30,000 個/μL 且出血不危及生命或不被認為是嚴重的;
血小板計數低於 100,000 個/μL 且伴有多發性創傷或顱內出血

遵循根據出血嚴重程度和具體情況制定的血小板輸注閾值,可優化患者的治療和預後。

預防性輸注閾值
當血小板計數低於特定閾值時,建議進行血小板輸注,作為特定操作前的預防措施或預防自發性出血。預防性輸注閾值如下表所示。
臨床背景血小板輸注閾值
自發性出血預防

<10,000 /μL

有些醫師建議 < 5000 /μL 才輸

神經外科手術或眼科手術前

<100,000 /μL
大型手術前<50,000 /μL
散播性血管內凝血<50,000 /μL
中心靜脈置管前<20,000 /μL 
硬脊膜外麻醉前<80,000 /μL
支氣管肺泡灌洗前<20,000-30,000 /μL 
內視鏡檢查前 

用於治療程序  <50,000/μL

低風險診斷程序< 20,000 /μL。

分娩期間 

陰道分娩時 <30,000/μL

剖腹產時 <50,000/μL  

腰椎穿刺前 

血癌患者 <10,000-20,000/μL

非血癌患者 40,000-50,000 /μL。


Platelet Transfusion Thresholds in Bleeding Patients

Platelet transfusion thresholds guide transfusion decisions based on severity and clinical context. The treatment is indicated in the following bleeding cases:Less than 50,000 cells/μL with severe bleeding, including disseminated intravascular coagulation
Less than 30,000 cells/μL when bleeding is not life-threatening or considered severe
Less than 100,000 cells/μL for bleeding in the context of multiple trauma or intracranial bleeding [8]

Adherence to platelet transfusion thresholds, tailored to bleeding severity and the circumstances, optimizes patient care and outcomes.

Prophylactic Transfusion Thresholds

Platelet transfusion is recommended when the platelet count falls below a certain threshold, either as a preventive measure before specific procedures or to prevent spontaneous bleeding. The prophylactic transfusion thresholds are outlined in the table below.
Clinical ContextPlatelet Transfusion Threshold
Spontaneous bleeding prevention

<10,000 cells/μL

Some authors recommend a threshold of 5000 cells/μL.

Before neurosurgery or ocular surgery

<100,000 cells/μL
Before major surgery<50,000 cells/μL
Disseminated intravascular coagulation<50,000 cells/μL
Before central line placement<20,000 cells/μL 
Before epidural anesthesia<80,000 cells/μL
Before bronchoalveolar lavage<20,000-30,000 cells/μL 
Before endoscopic procedures 

<50,000 cells/μL for therapeutic procedures

<20,000 cells/μL for low-risk diagnostic procedures

During parturition 

<30,000 cells/μL for a vaginal delivery

<50,000 cells/μL for a cesarean section 

Before lumbar puncture 

<10,000-20,000 cells/μL in hematologic malignancies

<40,000-50,000 cells/μL if without a hematologic malignancy

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