野外與登山醫學----05-Acute altitude illness WMS 2019 update AMS/HACE prevention Ginkgo biloba 5 (done)

Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Acute Altitude Illness: 2019 Update
統一名詞翻譯
AMS 急性高山病
HACE 高海拔腦水腫
acute altitude illness 急性高海拔疾病

Ginkgo biloba 銀杏萃取物, 有兩篇研究顯示銀杏有預防AMS功效, 但也有其他研究顯示無效, 結果差異或許與銀杏產品的來源及組成有關, 懷孕婦女應避免使用銀杏, 服用抗凝血劑的患者也需小心(可能會增加出血風險),. 對於預防AMS而言, 應該優先考慮使用丹木斯, 不建議使用銀杏萃取物作為預防AMS的方式, 證據等級1C

Although 2 trials demonstrated a benefit of Ginkgo in AMS prevention,35,36 2 other negative trials have also been published.37,38 This discrepancy may result from differences in the source and composition of the Ginkgo products.39 Ginkgo should be avoided in pregnant women40 and used with caution in people taking anticoagulants.41 Acetazolamide is considered far superior for AMS prevention. Recommendation. Ginkgo biloba should not be used for AMS prevention. Recommendation Grade: 1C