Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Acute Altitude Illness: 2019 Update
統一名詞翻譯
AMS 急性高山病
HACE 高海拔腦水腫
HAPE 高海拔肺水腫
acute altitude illness 急性高海拔疾病
Tadalafil
In a single, randomized placebo-controlled trial, 10 mg of
tadalafil every 12 h was effective in preventing HAPE in
susceptible individuals.85 The number of individuals in
the study was small, and 2 developed incapacitating
AMS. Clinical experience with tadalafil is lacking compared to nifedipine. As a result, further data are necessary
before tadalafil can be recommended over nifedipine.
Recommendation. Tadalafil can be used for HAPE prevention in known susceptible individuals who are not candidates for nifedipine. Recommendation Grade: 1C
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