野外與登山醫學---37-WMS 2019 update HAPE TREATMENT Dexamethasone 37

Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Acute Altitude Illness: 2019 Update
統一名詞翻譯
AMS 急性高山病
HACE 高海拔腦水腫
HAPE 高海拔肺水腫
acute altitude illness 急性高海拔疾病

過去的研究發現地塞米松(下面直接稱類固醇)可能有預防 HAPE的效果. 且會影響低血氧環境的最大運動耐力. 肺部發炎, 離子運輸功能. 有人猜測類固醇或許能用於治療 HAPE. 但目前尚無研究證實. 因此並未將類固醇放入HAPE治療選項. 

Dexamethasone地塞米松
Considering its potential role in HAPE prevention noted earlier and studies demonstrating effects on maximum exercise capacity,101 pulmonary inflammation, and ion transporter function in hypoxia,102 dexamethasone may have a role in HAPE treatment. Although reports document clinical use in this regard,98 no study has established whether it is effective for this purpose. Recommendation. Because of insufficient evidence, no recommendation can be made regarding dexamethasone for HAPE treatment.