野外與登山醫學---24---WMS 2019 update HAPE PREVENTION Dexamethasone 24

Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Acute Altitude Illness: 2019 Update
統一名詞翻譯
AMS 急性高山病
HACE 高海拔腦水腫
HAPE 高海拔肺水腫
acute altitude illness 急性高海拔疾病

Dexamethasone
In the same study that assessed the role of tadalafil in HAPE prevention, dexamethasone (8 mg every 12 h) was also found to prevent HAPE in susceptible individuals.85 The mechanism for this effect is not clear, and there is very little clinical experience in using dexamethasone for this purpose. Further data are necessary before it can be recommended for HAPE prevention. Recommendation. Dexamethasone can be used for HAPE prevention in known susceptible individuals who are not candidates for nifedipine and tadalafil. Recommendation Grade: 1C