野外與登山醫學----22---WMS 2019 update HAPE PREVENTION Salmeterol 22

Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Acute Altitude Illness: 2019 Update
統一名詞翻譯
AMS 急性高山病
HACE 高海拔腦水腫
HAPE 高海拔肺水腫
acute altitude illness 急性高海拔疾病

Salmeterol
In a single randomized, placebo-controlled study, the longacting inhaled beta-agonist salmeterol decreased the incidence of HAPE by 50% in susceptible individuals.84 Very high doses (125 micrograms twice daily) that are often associated with side effects, including tremor and tachycardia, were used in the study. Clinical experience with salmeterol at high altitude is limited. Recommendation. Salmeterol is not recommended for HAPE prevention. Recommendation Grade: 2B.